Stachybocins, novel endothelin receptor antagonists, produced by Stachybotrys sp. M6222. II. Structure determination of stachybocins A, B and C.

نویسندگان

  • K Ogawa
  • M Nakamura
  • M Hayashi
  • S Yaginuma
  • S Yamamoto
  • K Furihata
  • K Shin-Ya
  • H Seta
چکیده

The structures of stachybocins A, B and C, new endothelin receptor antagonist, were determined by NMR spectral analysis using pulse-field-gradient technique. Stachybocin A consists of two spirobenzofuran units each fused to a substituted decalin, which were connected by a lysine residue. Stachybocins B and C are derivatives of stachybocin A with an additional hydroxy group at the same position in the different decalin unit.

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عنوان ژورنال:
  • The Journal of antibiotics

دوره 48 12  شماره 

صفحات  -

تاریخ انتشار 1995